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Targeting virulence mechanisms for the prevention and therapy of arenaviral hemorrhagic fever

A number of arenaviruses are pathogenic for humans, but they differ significantly in virulence. Lassa virus, found in West Afri ca, causes severe hemorrhagic fever (HF), while the other principal Old World arenavirus, lymphocytic choriomeningitis virus, causes mild illness in persons with normal imm...

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Main Authors: McLay, Lisa, Ansari, Aftab, Liang, Yuying, Ly, Hinh
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563861/
https://ncbi.nlm.nih.gov/pubmed/23261843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2012.12.003
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