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Targeting virulence mechanisms for the prevention and therapy of arenaviral hemorrhagic fever

A number of arenaviruses are pathogenic for humans, but they differ significantly in virulence. Lassa virus, found in West Afri ca, causes severe hemorrhagic fever (HF), while the other principal Old World arenavirus, lymphocytic choriomeningitis virus, causes mild illness in persons with normal imm...

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Main Authors: McLay, Lisa, Ansari, Aftab, Liang, Yuying, Ly, Hinh
格式: Artigo
語言:Inglês
出版: 2012
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563861/
https://ncbi.nlm.nih.gov/pubmed/23261843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2012.12.003
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