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Decoupling chromatin and genetic effects through systematic analysis of gene position
Classic ‘position-effect’ experiments repositioned genes near telomeres to demonstrate that the epigenetic landscape can dramatically alter gene expression. Here we show that systematic gene knockout collections provide an exceptional resource for interrogating position effects, not only near telome...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3563736/ https://ncbi.nlm.nih.gov/pubmed/23291096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.12.003 |
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