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Systematic interpretation of genetic interactions using protein networks

Genetic interaction analysis, in which two mutations have a combined effect not exhibited by either mutation alone, is a powerful and widespread tool for establishing functional linkages between genes. In the yeast Saccharomyces cerevisiae, ongoing screens have generated >4,800 such genetic inter...

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Detalhes bibliográficos
Main Authors: Kelley, Ryan, Ideker, Trey
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814446/
https://ncbi.nlm.nih.gov/pubmed/15877074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt1096
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