Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression

Androgen receptor (AR) signaling plays a critical role in prostate cancer (PCA) pathogenesis. Yet, the regulation of AR signaling remains elusive. Even with stringent androgen deprivation therapy, AR signaling persists. Here, our data suggest that there is a complex interaction between the expressio...

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Hlavní autoři: Lin, Pei-Chun, Chiu, Ya-Lin, Banerjee, Samprit, Park, Kyung, Mosquera, Juan Miguel, Giannopoulou, Eugenia, Alves, Pedro, Tewari, Ashutosh K., Gerstein, Mark B., Beltran, Himisha, Melnick, Ari M., Elemento, Olivier, Demichelis, Francesca, Rubin, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563734/
https://ncbi.nlm.nih.gov/pubmed/23233736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2968
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