Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression

Androgen receptor (AR) signaling plays a critical role in prostate cancer (PCA) pathogenesis. Yet, the regulation of AR signaling remains elusive. Even with stringent androgen deprivation therapy, AR signaling persists. Here, our data suggest that there is a complex interaction between the expressio...

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Detalhes bibliográficos
Main Authors: Lin, Pei-Chun, Chiu, Ya-Lin, Banerjee, Samprit, Park, Kyung, Mosquera, Juan Miguel, Giannopoulou, Eugenia, Alves, Pedro, Tewari, Ashutosh K., Gerstein, Mark B., Beltran, Himisha, Melnick, Ari M., Elemento, Olivier, Demichelis, Francesca, Rubin, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563734/
https://ncbi.nlm.nih.gov/pubmed/23233736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2968
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