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Interleukin-4-induced β-catenin regulates the conversion of macrophages to multinucleated giant cells

The cytokine interleukin-4 (IL-4) exerts pleiotropic effects on macrophages as it plays a key role in the immune response to infectious agents, allergens, and vaccines. Macrophages exposed to IL-4 drastically change their gene expression and metabolic state to adjust to new functional requirements....

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Detalhes bibliográficos
Main Authors: Binder, Flora, Hayakawa, Morisada, Choo, Min-Kyung, Sano, Yasuyo, Park, Jin Mo
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563716/
https://ncbi.nlm.nih.gov/pubmed/23287596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.12.004
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