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Intravenous Delivery of HIV-Based Lentiviral Vectors Preferentially Transduces F4/80+ and Ly-6C+ Cells in Spleen, Important Target Cells in Autoimmune Arthritis

Antigen presenting cells (APCs) play an important role in arthritis and APC specific gene therapeutic targeting will enable intracellular modulation of cell activity. Viral mediated overexpression is a potent approach to achieve adequate transgene expression levels and lentivirus (LV) is useful for...

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Xehetasun bibliografikoak
Egile Nagusiak: van den Brand, Ben T., Vermeij, Eline A., Waterborg, Claire E. J., Arntz, Onno J., Kracht, Michael, Bennink, Miranda B., van den Berg, Wim B., van de Loo, Fons A. J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563527/
https://ncbi.nlm.nih.gov/pubmed/23390530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055356
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