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Association of telomere instability with senescence of porcine cells

BACKGROUND: Telomeres are essential for the maintenance of genomic stability, and telomere dysfunction leads to cellular senescence, carcinogenesis, aging, and age-related diseases in humans. Pigs have become increasingly important large animal models for preclinical tests and study of human disease...

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Detalhes bibliográficos
Main Authors: Ji, Guangzhen, Liu, Kai, Okuka, Maja, Liu, Na, Liu, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563453/
https://ncbi.nlm.nih.gov/pubmed/23241441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-13-36
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