Effect of High-Dose or Split-Dose Artesunate on Parasite Clearance in Artemisinin-Resistant Falciparum Malaria

Background. The emergence of Plasmodium falciparum resistance to artemisinins on the Cambodian and Myanmar-Thai borders poses severe threats to malaria control. We investigated whether increasing or splitting the dose of the short-half-life drug artesunate improves parasite clearance in falciparum m...

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Hauptverfasser: Das, Debashish, Tripura, Rupam, Phyo, Aung Pyae, Lwin, Khin Maung, Tarning, Joel, Lee, Sue J., Hanpithakpong, Warunee, Stepniewska, Kasia, Menard, Didier, Ringwald, Pascal, Silamut, Kamolrat, Imwong, Mallika, Chotivanich, Kesinee, Yi, Poravuth, Day, Nicholas P. J., Lindegardh, Niklas, Socheat, Duong, Nguon, Chea, White, Nicholas J., Nosten, François, Dondorp, Arjen M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
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Electronic Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563392/
https://ncbi.nlm.nih.gov/pubmed/23175556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cis958
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