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Normobaric hyperoxia combined with minocycline provides greater neuroprotection than either alone in transient focal cerebral ischemia

Normobaric hyperoxia (NBO), which maintains penumbral oxygenation, reduces brain injury during cerebral ischemia, and minocycline, a tetracycline derivative, reduces reperfusion injury, including inflammation, apoptosis and matrix metalloproteinases (MMPs) activation. Since they have different mecha...

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Detalhes bibliográficos
Main Authors: Jin, Xinchun, Liu, Jie, Liu, Ke J., Rosenberg, Gary A., Yang, Yi, Liu, Wenlan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563388/
https://ncbi.nlm.nih.gov/pubmed/23195595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.11.018
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