Normobaric hyperoxia combined with minocycline provides greater neuroprotection than either alone in transient focal cerebral ischemia

Normobaric hyperoxia (NBO), which maintains penumbral oxygenation, reduces brain injury during cerebral ischemia, and minocycline, a tetracycline derivative, reduces reperfusion injury, including inflammation, apoptosis and matrix metalloproteinases (MMPs) activation. Since they have different mecha...

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Autori principali: Jin, Xinchun, Liu, Jie, Liu, Ke J., Rosenberg, Gary A., Yang, Yi, Liu, Wenlan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563388/
https://ncbi.nlm.nih.gov/pubmed/23195595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.11.018
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