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The effect of 2-methoxyestradiol, a HIF-1α inhibitor, in global cerebral ischemia in rats
Global cerebral ischemia is an important clinical problem with few effective treatments. The hippocampus, which is important for memory, is especially vulnerable during global ischemia. Brain-specific knockout of hypoxia inducible factor-1α (HIF-1α) has been shown to be protective in focal ischemia...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3563278/ https://ncbi.nlm.nih.gov/pubmed/17716391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/016164107X229920 |
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