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The effect of 2-methoxyestradiol, a HIF-1α inhibitor, in global cerebral ischemia in rats

Global cerebral ischemia is an important clinical problem with few effective treatments. The hippocampus, which is important for memory, is especially vulnerable during global ischemia. Brain-specific knockout of hypoxia inducible factor-1α (HIF-1α) has been shown to be protective in focal ischemia...

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Hlavní autoři: Zhou, Dachun, Matchett, Gerald A., Jadhav, Vikram, Dach, Neal, Zhang, John H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563278/
https://ncbi.nlm.nih.gov/pubmed/17716391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/016164107X229920
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