Genetic variation in radiation and platinum pathways predicts severe acute radiation toxicity in patients with esophageal adenocarcinoma treated with cisplatin-based preoperative radiochemotherapy: results from the Eastern Cooperative Oncology Group

PURPOSE: Germline genetic variations may partly explain the clinical observation that normal tissue tolerance to radiochemotherapy varies by individual. Our objective was to evaluate the association between single-nucleotide polymorphisms (SNPs) in radiation/platinum pathways and serious treatment-r...

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Detalhes bibliográficos
Main Authors: Yoon, H. H., Catalano, P., Gibson, M. K., Skaar, T. C., Philips, S., Montgomery, E. A., Hafez, M. J., Powell, M., Liu, G., Forastiere, A. A., Benson, A. B., Kleinberg, L. R., Murphy, K. M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563156/
https://ncbi.nlm.nih.gov/pubmed/21286719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-011-1556-5
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