Genetic variation in DNA-repair pathways and response to radiochemotherapy in esophageal adenocarcinoma: a retrospective cohort study of the Eastern Cooperative Oncology Group

BACKGROUND: Recent data in esophageal cancer suggests the variant allele of a single-nucleotide polymorphism (SNP) in XRCC1 may be associated with resistance to radiochemotherapy. However, this SNP has not been assessed in a histologically homogeneous clinical trial cohort that has been treated with...

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Main Authors: Yoon, Harry H, Catalano, Paul J, Murphy, Kathleen M, Skaar, Todd C, Philips, Santosh, Powell, Mark, Montgomery, Elizabeth A, Hafez, Michael J, Offer, Steven M, Liu, Geoffrey, Meltzer, Stephen J, Wu, Xifeng, Forastiere, Arlene A, Benson, Al B, Kleinberg, Lawrence R, Gibson, Michael K
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118194/
https://ncbi.nlm.nih.gov/pubmed/21586140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-176
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