Effect of Spironolactone and Amiloride on Thiazolidinedione-Induced Fluid Retention in South Indian Patients with Type 2 Diabetes

BACKGROUND AND OBJECTIVES: Thiazolidinediones (pioglitazone and rosiglitazone) induce renal epithelial sodium channel (ENaC)–mediated sodium reabsorption, resulting in plasma volume (PV) expansion. Incidence and long-term management of fluid retention induced by thiazolidinediones remain unclear. DE...

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Autors principals: Viswanathan, Vijay, Mohan, Viswanathan, Subramani, Poongothai, Parthasarathy, Nandakumar, Subramaniyam, Gayathri, Manoharan, Deepa, Sundaramoorthy, Chandru, Gnudi, Luigi, Karalliedde, Janaka, Viberti, Giancarlo
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2013
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562862/
https://ncbi.nlm.nih.gov/pubmed/23184569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.06330612
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