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Effect of Renin-Angiotensin System Blockade on Soluble Klotho in Patients with Type 2 Diabetes, Systolic Hypertension, and Albuminuria

BACKGROUND AND OBJECTIVES: Soluble Klotho is an anti-aging phosphaturic protein associated with vascular-renal protection. In vitro and in vivo studies have demonstrated that renin-angiotensin system (RAS) blockade increases soluble Klotho levels. The effect of RAS blockers on soluble Klotho in pati...

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Detalhes bibliográficos
Main Authors: Karalliedde, Janaka, Maltese, Giuseppe, Hill, Benjamin, Viberti, Giancarlo, Gnudi, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817905/
https://ncbi.nlm.nih.gov/pubmed/23929932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.02700313
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