Long-term in vivo monitoring of mouse and human hematopoietic stem cell engraftment with a human positron emission tomography reporter gene

Positron emission tomography (PET) reporter genes allow noninvasive whole-body imaging of transplanted cells by detection with radiolabeled probes. We used a human deoxycytidine kinase containing three amino acid substitutions within the active site (hdCK3mut) as a reporter gene in combination with...

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Detalhes bibliográficos
Main Authors: McCracken, Melissa N., Gschweng, Eric H., Nair-Gill, Evan, McLaughlin, Jami, Cooper, Aaron R., Riedinger, Mireille, Cheng, Donghui, Nosala, Christopher, Kohn, Donald B., Witte, Owen N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562822/
https://ncbi.nlm.nih.gov/pubmed/23319634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221840110
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