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Two-gate mechanism for phospholipid selection and transport by type IV P-type ATPases

Most P-type ATPases pump specific cations or heavy metals across a membrane to form ion gradients. However, the type IV P-type ATPases evolved the ability to transport specific phospholipid substrates rather than cations and function to establish plasma membrane asymmetry in eukaryotic cells. The me...

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Autori principali: Baldridge, Ryan D., Graham, Todd R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562821/
https://ncbi.nlm.nih.gov/pubmed/23302692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216948110
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