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NTP-mediated nucleotide excision activity of hepatitis C virus RNA-dependent RNA polymerase
Hepatitis C virus (HCV) RNA-dependent RNA polymerase replicates the viral genomic RNA and is a primary drug target for antiviral therapy. Previously, we described the purification of an active and stable polymerase–primer–template elongation complex. Here, we show that, unexpectedly, the polymerase...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3562815/ https://ncbi.nlm.nih.gov/pubmed/23307808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214924110 |
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