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Buried lysine, but not arginine, titrates and alters transmembrane helix tilt
The ionization states of individual amino acid residues of membrane proteins are difficult to decipher or assign directly in the lipid–bilayer membrane environment. We address this issue for lysines and arginines in designed transmembrane helices. For lysines (but not arginines) at two locations wit...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3562795/ https://ncbi.nlm.nih.gov/pubmed/23319623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215400110 |
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