Deficiency in Metabolic Regulators PPARγ and PTEN Cooperates to Drive Keratinizing Squamous Metaplasia in Novel Models of Human Tissue Regeneration

Hindgut-derived endoderm can differentiate into rectal, prostatic, and bladder phenotypes. Stromal-epithelial interactions are crucial for this development; however, the precise mechanisms by which epithelium responds to stromal cues remain unknown. We have previously reported ectopic expression of...

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Detalhes bibliográficos
Main Authors: Strand, Douglas W., DeGraff, David J., Jiang, Ming, Sameni, Mansoureh, Franco, Omar E., Love, Harold D., Hayward, William J., Lin-Tsai, Opal, Wang, Anne Y., Cates, Justin M.M., Sloane, Bonnie F., Matusik, Robert J., Hayward, Simon W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562729/
https://ncbi.nlm.nih.gov/pubmed/23219716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.10.007
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