Transcriptome-wide miR-155 binding map reveals widespread non-canonical microRNA targeting

microRNAs (miRNAs) are essential components of gene regulation, but identification of miRNA targets remains a major challenge. Most target prediction and discovery relies on perfect complementarity of the miRNA seed to the 3′ untranslated region (UTR). However, it is unclear to what extent miRNAs ta...

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Autori principali: Loeb, Gabriel B., Khan, Aly A., Canner, David, Hiatt, Joseph B., Shendure, Jay, Darnell, Robert B., Leslie, Christina S., Rudensky, Alexander Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562697/
https://ncbi.nlm.nih.gov/pubmed/23142080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.10.002
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