Evaluation of phosphatidylinositol-3-kinase catalytic subunit (PIK3CA) and epidermal growth factor receptor (EGFR) gene mutations in pancreaticobiliary adenocarcinoma

BACKGROUND: Phosphatidylinositol-3-kinase (PI3K) activation involves the epidermal growth factor receptor (EGFR) and plays an important role in cell survival signaling in pancreaticobiliary cancer. EGFR gene mutations have been correlated with clinical response to EGFR inhibitors in patients with ad...

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Detalhes bibliográficos
Main Authors: Weiss, Guy A., Rossi, Michael R., Khushalani, Nikhil I., Lo, Ken, Gibbs, John F., Bharthuar, Anubha, Cowell, John K., Iyer, Renuka
Formato: Artigo
Idioma:Inglês
Publicado em: Pioneer Bioscience Publishing Company 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562624/
https://ncbi.nlm.nih.gov/pubmed/23450128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2078-6891.2012.012
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