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Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development
Mammalian SWI/SNF complexes utilize either BRG1 or BRM as alternative catalytic subunits with DNA-dependent ATPase activity to remodel chromatin. Although the two proteins are 75% identical, broadly expressed, and have similar biochemical activities in vitro, BRG1 is essential for mouse embryonic de...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3562406/ https://ncbi.nlm.nih.gov/pubmed/23076393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-012-9433-z |
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