Cardiotoxic and Cardioprotective Features of Chronic β-adrenergic Signaling

RATIONALE: In the failing heart, persistent β-adrenergic receptor (βAR) activation is thought to induce myocyte death by protein kinase A (PKA)-dependent and PKA-independent activation of calcium/calmodulin-dependent kinase II (CaMKII). β-Adrenergic signaling pathways are also capable of activating...

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Hauptverfasser: Zhang, Xiaoying, Szeto, Christopher, Gao, Erhe, Tang, Mingxin, Jin, Jianguo, Fu, Qin, Makarewich, Catherine, Ai, Xiaojie, Li, Ying, Tang, Allen, Wang, Jenny, Gao, Hui, Wang, Fang, Ge, Xinyi Joy, Kunapuli, Satya P., Zhou, Lin, Zeng, Chunyu, Xiang, Kevin Yang, Chen, Xiongwen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562387/
https://ncbi.nlm.nih.gov/pubmed/23104882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.273896
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