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PAIR: paired allelic log-intensity-ratio-based normalization method for SNP-CGH arrays
Motivation: Normalization is critical in DNA copy number analysis. We propose a new method to correctly identify two-copy probes from the genome to obtain representative references for normalization in single nucleotide polymorphism arrays. The method is based on a two-state Hidden Markov Model. Unl...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3562063/ https://ncbi.nlm.nih.gov/pubmed/23196989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts683 |
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