Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios

BACKGROUND: Illumina Infinium whole genome genotyping (WGG) arrays are increasingly being applied in cancer genomics to study gene copy number alterations and allele-specific aberrations such as loss-of-heterozygosity (LOH). Methods developed for normalization of WGG arrays have mostly focused on di...

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Bibliographische Detailangaben
Hauptverfasser: Staaf, Johan, Vallon-Christersson, Johan, Lindgren, David, Juliusson, Gunnar, Rosenquist, Richard, Höglund, Mattias, Borg, Åke, Ringnér, Markus
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2008
Schlagworte:
Methodology Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572624/
https://ncbi.nlm.nih.gov/pubmed/18831757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-409
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