Transcription blockage by homopurine DNA sequences: role of sequence composition and single-strand breaks

The ability of DNA to adopt non-canonical structures can affect transcription and has broad implications for genome functioning. We have recently reported that guanine-rich (G-rich) homopurine-homopyrimidine sequences cause significant blockage of transcription in vitro in a strictly orientation-dep...

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Detalles Bibliográficos
Autores principales: Belotserkovskii, Boris P., Neil, Alexander J., Saleh, Syed Shayon, Shin, Jane Hae Soo, Mirkin, Sergei M., Hanawalt, Philip C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
Materias:
Molecular Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561996/
https://ncbi.nlm.nih.gov/pubmed/23275544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1333
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