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Vaccinia and influenza A viruses select rather than adjust tRNAs to optimize translation

Transfer RNAs (tRNAs) are central to protein synthesis and impact translational speed and fidelity by their abundance. Here we examine the extent to which viruses manipulate tRNA populations to favor translation of their own genes. We study two very different viruses: influenza A virus (IAV), a medi...

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Detalhes bibliográficos
Main Authors: Pavon-Eternod, Mariana, David, Alexandre, Dittmar, Kimberly, Berglund, Peter, Pan, Tao, Bennink, Jack R., Yewdell, Jonathan W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561966/
https://ncbi.nlm.nih.gov/pubmed/23254333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks986
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