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Loss of SPARC in bladder cancer enhances carcinogenesis and progression

Secreted protein acidic and rich in cysteine (SPARC) has been implicated in multiple aspects of human cancer. However, its role in bladder carcinogenesis and metastasis are unclear,with some studies suggesting it may be a promoter and others arguing the opposite. Using a chemical carcinogenesis mode...

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Autors principals: Said, Neveen, Frierson, Henry F., Sanchez-Carbayo, Marta, Brekken, Rolf A., Theodorescu, Dan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561835/
https://ncbi.nlm.nih.gov/pubmed/23321672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64782
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