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Tumor endothelin-1 enhances metastatic colonization of the lung in mouse xenograft models of bladder cancer
Many patients with advanced bladder cancer develop lethal metastases to the lung. The vasoconstricting protein endothelin-1 (ET-1) has been implicated in this process, although the mechanism(s) by which it promotes metastasis remains unclear. Here, we have evaluated whether tumor ET-1 expression can...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3007145/ https://ncbi.nlm.nih.gov/pubmed/21183790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42912 |
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