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Activin receptor inhibition by Smad2 regulates Drosophila wing disc patterning through BMP-response elements

Imaginal disc development in Drosophila requires coordinated cellular proliferation and tissue patterning. In our studies of TGFβ superfamily signaling components, we found that a protein null mutation of Smad2, the only Activin subfamily R-Smad in the fruit fly, produces overgrown wing discs that r...

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Bibliografiske detaljer
Main Authors: Peterson, Aidan J., O'Connor, Michael B.
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561785/
https://ncbi.nlm.nih.gov/pubmed/23293296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.085605
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