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Multiple Metal Binding Domains Enhance the Zn(II) Selectivity of the Divalent Metal Ion Transporter AztA()

Transition metal-transporting P(1B)-type CPx ATPases play crucial roles in mediating metal homeostasis and resistance in all cells. The degree to which N-terminal metal binding domains (MBDs) confer metal specificity to the transporter is unclear. We show that the two MBDs of the Zn/Cd/Pb effluxing...

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Detalhes bibliográficos
Main Authors: Liu, Tong, Reyes-Caballero, Hermes, Li, Chenxi, Scott, Robert A., Giedroc, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561713/
https://ncbi.nlm.nih.gov/pubmed/17824670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7006367
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