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Pharmacokinetic Interaction Between Prasugrel and Ritonavir in Healthy Volunteers
The new anti-aggregating agent prasugrel is bioactivated by cytochromes P450 (CYP) 3A and 2B6. Ritonavir is a potent CYP3A inhibitor and was shown in vitro as a CYP2B6 inhibitor. The aim of this open-label cross-over study was to assess the effect of ritonavir on prasugrel active metabolite (prasugr...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Blackwell Publishing Ltd
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561686/ https://ncbi.nlm.nih.gov/pubmed/22900583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-7843.2012.00932.x |
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