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End-resection at DNA double-strand breaks in the three domains of life

During DNA repair by HR (homologous recombination), the ends of a DNA DSB (double-strand break) must be resected to generate single-stranded tails, which are required for strand invasion and exchange with homologous chromosomes. This 5′–3′ end-resection of the DNA duplex is an essential process, con...

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Detalhes bibliográficos
Main Authors: Blackwood, John K., Rzechorzek, Neil J., Bray, Sian M., Maman, Joseph D., Pellegrini, Luca, Robinson, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561678/
https://ncbi.nlm.nih.gov/pubmed/23356304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20120307
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