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Functional Requirement for a Highly Conserved Charged Residue at Position 75 in the Gap Junction Protein Connexin 32

Charcot Marie Tooth disease (CMT) is a group of inherited disorders characterized clinically by exclusively or predominantly peripheral nerve dysfunction. CMT1X, the most common form of X-linked CMT is caused by mutations in connexin 32 (Cx32). In this work, we used dual whole cell patch clamp recor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Abrams, Charles K., Islam, Mahee, Mahmoud, Rola, Kwon, Taekyung, Bargiello, Thaddeus A., Freidin, Mona M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561579/
https://ncbi.nlm.nih.gov/pubmed/23209285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.392670
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