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A Positive Feedback Loop Regulates the Expression of Polycomb Group Protein BMI1 via WNT Signaling Pathway

Polycomb group protein BMI1 plays an important role in cellular homeostasis by maintaining a balance between proliferation and senescence. It is often overexpressed in cancer cells and is required for self-renewal of stem cells. At present, very little is known about the signaling pathways that regu...

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מידע ביבליוגרפי
Main Authors: Cho, Joon-Ho, Dimri, Manjari, Dimri, Goberdhan P.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561559/
https://ncbi.nlm.nih.gov/pubmed/23239878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.422931
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