Platelet factor 4 induces cell apoptosis by inhibition of STAT3 via up-regulation of SOCS3 expression in multiple myeloma

Platelet factor 4 (PF4) is an angiostatic chemokine that suppresses tumor growth and metastasis. We previously revealed frequent transcriptional silencing of PF4 in multiple myeloma, but the functional roles of this chemokine are still unknown. We studied the apoptotic effects of PF4 on myeloma cell...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liang, Pei, Cheng, Suk Hang, Cheng, Chi Keung, Lau, Kin Mang, Lin, Shek Ying, Chow, Eudora Y.D., Chan, Natalie P.H., Ip, Rosalina K.L., Wong, Raymond S.M., Ng, Margaret H. L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ferrata Storti Foundation 2013
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561438/
https://ncbi.nlm.nih.gov/pubmed/22929979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.065607
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg