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Histone acetylation and DNA demethylation of T cells result in an anaplastic large cell lymphoma-like phenotype

A characteristic feature of anaplastic large cell lymphoma is the significant repression of the T-cell expression program despite its T-cell origin. The reasons for this down-regulation of T-cell phenotype are still unknown. To elucidate whether epigenetic mechanisms are responsible for the loss of...

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Detalhes bibliográficos
Main Authors: Joosten, Maria, Seitz, Volkhard, Zimmermann, Karin, Sommerfeld, Anke, Berg, Erika, Lenze, Dido, Leser, Ulf, Stein, Harald, Hummel, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561432/
https://ncbi.nlm.nih.gov/pubmed/22899583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.054619
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