Histone H3K4 demethylation is negatively regulated by histone H3 acetylation in Saccharomyces cerevisiae

Histone H3 lysine 4 trimethylation (H3K4me3) is a hallmark of transcription initiation, but how H3K4me3 is demethylated during gene repression is poorly understood. Jhd2, a JmjC domain protein, was recently identified as the major H3K4me3 histone demethylase (HDM) in Saccharomyces cerevisiae. Althou...

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Detalhes bibliográficos
Main Authors: Maltby, Vicki E., Martin, Benjamin J. E., Brind’Amour, Julie, Chruscicki, Adam T., McBurney, Kristina L., Schulze, Julia M., Johnson, Ian J., Hills, Mark, Hentrich, Thomas, Kobor, Michael S., Lorincz, Matthew C., Howe, LeAnn J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494965/
https://ncbi.nlm.nih.gov/pubmed/23091032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202070109
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