Combining Functional and Structural Genomics to Sample the Essential Burkholderia Structome

BACKGROUND: The genus Burkholderia includes pathogenic gram-negative bacteria that cause melioidosis, glanders, and pulmonary infections of patients with cancer and cystic fibrosis. Drug resistance has made development of new antimicrobials critical. Many approaches to discovering new antimicrobials...

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Autores principales: Baugh, Loren, Gallagher, Larry A., Patrapuvich, Rapatbhorn, Clifton, Matthew C., Gardberg, Anna S., Edwards, Thomas E., Armour, Brianna, Begley, Darren W., Dieterich, Shellie H., Dranow, David M., Abendroth, Jan, Fairman, James W., Fox, David, Staker, Bart L., Phan, Isabelle, Gillespie, Angela, Choi, Ryan, Nakazawa-Hewitt, Steve, Nguyen, Mary Trang, Napuli, Alberto, Barrett, Lynn, Buchko, Garry W., Stacy, Robin, Myler, Peter J., Stewart, Lance J., Manoil, Colin, Van Voorhis, Wesley C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561365/
https://ncbi.nlm.nih.gov/pubmed/23382856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053851
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