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The Oxidative Modification of Von Willebrand Factor Is Associated with Thrombotic Angiopathies in Diabetes Mellitus

The thrombogenic activity of Von Willebrand factor (VWF) is proportional to its molecular size and inversely related to its proteolysis by ADAMTS-13. Oxidation of VWF severely impairs its proteolysis by the metalloprotease. This study was aimed at assessing in patients with type 1 and type 2 diabete...

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מידע ביבליוגרפי
Main Authors: Oggianu, Laura, Lancellotti, Stefano, Pitocco, Dario, Zaccardi, Francesco, Rizzo, Paola, Martini, Francesca, Ghirlanda, Giovanni, De Cristofaro, Raimondo
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561310/
https://ncbi.nlm.nih.gov/pubmed/23383177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055396
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