The Oxidative Modification of Von Willebrand Factor Is Associated with Thrombotic Angiopathies in Diabetes Mellitus

The thrombogenic activity of Von Willebrand factor (VWF) is proportional to its molecular size and inversely related to its proteolysis by ADAMTS-13. Oxidation of VWF severely impairs its proteolysis by the metalloprotease. This study was aimed at assessing in patients with type 1 and type 2 diabete...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Oggianu, Laura, Lancellotti, Stefano, Pitocco, Dario, Zaccardi, Francesco, Rizzo, Paola, Martini, Francesca, Ghirlanda, Giovanni, De Cristofaro, Raimondo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561310/
https://ncbi.nlm.nih.gov/pubmed/23383177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055396
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