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An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation and Virus Replication

Ebolaviruses, highly lethal zoonotic pathogens, possess longer genomes than most other non-segmented negative-strand RNA viruses due in part to long 5′ and 3′ untranslated regions (UTRs) present in the seven viral transcriptional units. To date, specific functions have not been assigned to these UTR...

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Autors principals: Shabman, Reed S., Hoenen, Thomas, Groseth, Allison, Jabado, Omar, Binning, Jennifer M., Amarasinghe, Gaya K., Feldmann, Heinz, Basler, Christopher F.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561295/
https://ncbi.nlm.nih.gov/pubmed/23382680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003147
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