An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation and Virus Replication

Ebolaviruses, highly lethal zoonotic pathogens, possess longer genomes than most other non-segmented negative-strand RNA viruses due in part to long 5′ and 3′ untranslated regions (UTRs) present in the seven viral transcriptional units. To date, specific functions have not been assigned to these UTR...

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Bibliografiske detaljer
Main Authors: Shabman, Reed S., Hoenen, Thomas, Groseth, Allison, Jabado, Omar, Binning, Jennifer M., Amarasinghe, Gaya K., Feldmann, Heinz, Basler, Christopher F.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561295/
https://ncbi.nlm.nih.gov/pubmed/23382680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003147
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