Discovery of a Siderophore Export System Essential for Virulence of Mycobacterium tuberculosis

Iron is an essential nutrient for most bacterial pathogens, but is restricted by the host immune system. Mycobacterium tuberculosis (Mtb) utilizes two classes of small molecules, mycobactins and carboxymycobactins, to capture iron from the human host. Here, we show that an Mtb mutant lacking the mmp...

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Main Authors: Wells, Ryan M., Jones, Christopher M., Xi, Zhaoyong, Speer, Alexander, Danilchanka, Olga, Doornbos, Kathryn S., Sun, Peibei, Wu, Fangming, Tian, Changlin, Niederweis, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561183/
https://ncbi.nlm.nih.gov/pubmed/23431276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003120
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