Binding of HIV-1 gp120 to DC-SIGN Promotes ASK-1-Dependent Activation-Induced Apoptosis of Human Dendritic Cells

During disease progression to AIDS, HIV-1 infected individuals become increasingly immunosuppressed and susceptible to opportunistic infections. It has also been demonstrated that multiple subsets of dendritic cells (DC), including DC-SIGN(+) cells, become significantly depleted in the blood and lym...

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Main Authors: Chen, Yongxiong, Hwang, Shiuh-Lin, Chan, Vera S. F., Chung, Nancy P. Y., Wang, Shu-Rong, Li, Zhongye, Ma, Jing, Lin, Chia-Wei, Hsieh, Ya-Ju, Chang, Kao-Ping, Kung, Sui-Sum, Wu, Yi-Chia, Chu, Cheng-Wei, Tai, Hsiao-Ting, Gao, George F., Zheng, Bojian, Yokoyama, Kazunari K., Austyn, Jonathan M., Lin, Chen-Lung S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561151/
https://ncbi.nlm.nih.gov/pubmed/23382671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003100
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