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An Incompatibility between a Mitochondrial tRNA and Its Nuclear-Encoded tRNA Synthetase Compromises Development and Fitness in Drosophila

Mitochondrial transcription, translation, and respiration require interactions between genes encoded in two distinct genomes, generating the potential for mutations in nuclear and mitochondrial genomes to interact epistatically and cause incompatibilities that decrease fitness. Mitochondrial-nuclear...

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Detalhes bibliográficos
Principais autores: Meiklejohn, Colin D., Holmbeck, Marissa A., Siddiq, Mohammad A., Abt, Dawn N., Rand, David M., Montooth, Kristi L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561102/
https://ncbi.nlm.nih.gov/pubmed/23382693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003238
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