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An Incompatibility between a Mitochondrial tRNA and Its Nuclear-Encoded tRNA Synthetase Compromises Development and Fitness in Drosophila

Mitochondrial transcription, translation, and respiration require interactions between genes encoded in two distinct genomes, generating the potential for mutations in nuclear and mitochondrial genomes to interact epistatically and cause incompatibilities that decrease fitness. Mitochondrial-nuclear...

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書誌詳細
主要な著者: Meiklejohn, Colin D., Holmbeck, Marissa A., Siddiq, Mohammad A., Abt, Dawn N., Rand, David M., Montooth, Kristi L.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561102/
https://ncbi.nlm.nih.gov/pubmed/23382693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003238
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