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Active site assembly in glutaminyl-tRNA synthetase by tRNA-mediated induced fit
Structure-based mutational analysis was employed to probe an unusual intramolecular interaction between partially buried glutamate residues adjacent to the active site of Escherichia coli glutaminyl-tRNA synthetase (GlnRS). Crystal structures of unliganded GlnRS and of the GlnRS-tRNA(Gln) complex re...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516378/ https://ncbi.nlm.nih.gov/pubmed/16734422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi052606b |
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