Ginkgolic acid inhibits HIV protease activity and HIV infection in vitro

BACKGROUND: Several HIV protease mutations, which are resistant to clinical HIV protease inhibitors (PIs), have been identified. There is a great need for second-generation PIs with different chemical structures and/or with an alternative mode of inhibition. Ginkgolic acid is a natural herbal substa...

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Bibliografiske detaljer
Main Authors: Lü, Jian-Ming, Yan, Shaoyu, Jamaluddin, Saha, Weakley, Sarah M., Liang, Zhengdong, Siwak, Edward B., Yao, Qizhi, Chen, Changyi
Format: Artigo
Sprog:Inglês
Udgivet: International Scientific Literature, Inc. 2012
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560711/
https://ncbi.nlm.nih.gov/pubmed/22847190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.883261
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